The protests were sparked by the ongoing fuel shortage across the country and alleged corruption in President Jovenel Moïse’s government.
A police station, shops and banks were reportedly attacked by the protesters on Friday. One building was set ablaze and major roads in the city were barricaded.
The police responded to the unrest by firing live ammunition and teargas.
Four people have since been killed in the violent protests.
While addressing the US General assembly on Wednesday, President Moïse appealed for calm in the country. His speech, however, failed to reduce tension in the Caribbean country.
The president rejected calls for his resignation earlier this year.